Sit up or stand slowly to reduce the risk of dizzy or fainting spells. Drinking alcohol with this medication can increase the risk of these side effects. This medication may be sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

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This makes it easier for individuals to reduce or abstain from alcohol use over time. In 2021, over 6,300 deaths in North Carolina were attributed to excessive alcohol use, making it the third leading preventable cause of death in the state according to the NC DHHS. Thus showing the significant need for medications that help with alcohol abuse. If you’re struggling with an opioid or alcohol addiction, naltrexone treatment could be beneficial as part of your treatment plan.
- Consequences may include problems with family or friends, problems at work, or negative physical and mental health impacts.
- The average values of right and left ROIs were used to increase the signal-to-noise ratio for the quantification.
- This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors.
- If you experience any symptoms that feel unusual or concerning, contact your healthcare provider right away.
- In fact, naltrexone is an opioid antagonist, meaning it binds to opioid receptors in the brain, blocking the effect of opioids.
- With drugs that are addictive, you may have trouble stopping use of the drug.
Is naltrexone used long term?
- People with AUD are unable to cut back or stop drinking despite its harmful effects on multiple areas of their daily life.
- To learn more about your treatment options, including inpatient facilities that utilize naltrexone, contact a treatment provider today.
The program may include counseling, psychotherapy, education, and support groups. In fact, because it’s an opioid antagonist, it can block the effect of opioid pain relievers. A combination medication containing naltrexone and bupropion (Contrave) is FDA-approved for weight loss. However, naltrexone isn’t typically prescribed on its own for this use. To learn more about taking Contrave for weight loss, talk with your doctor. Naheed Ali, MD, PhD, ScD, is a physician by education and a writer by choice.

Naltrexone: Definition, Mechanism of Action, Uses, Dosage, Side Effects, Alternatives
It supports relapse prevention by eliminating the pleasurable effects of alcohol and opioids, helping patients remain abstinent. Individuals with opioid use disorder who receive extended-release naltrexone are less likely to relapse when actively engaged in therapy. In Alcoholics Anonymous alcohol use disorder, naltrexone has been shown to significantly reduce cravings and drinking frequency, especially when combined with behavioral interventions. Alcohol Use Disorder (AUD) is a common medical condition that around 30 million Americans experience. People with AUD have trouble stopping or controlling their alcohol use despite negative consequences from drinking. Consequences may include problems with family or friends, problems at work, or negative physical and mental health impacts.
Serious side effects
Also tell them if you smoke, drink alcohol, or use illegal drugs. It works by blocking the effect of opioids and reducing cravings to use opioids. It is most effective when used in combination with counseling and behavior therapy. Yes, you can drink alcohol while on naltrexone because the medication does not cause illness upon alcohol consumption, unlike disulfiram. Instead, naltrexone reduces the rewarding effects of alcohol, helping to decrease cravings and the desire to drink.
Therefore, naltrexone treatment is started after you are no longer taking opioids for a period of time. The length of time this takes may depend on which opioid you took, the amount you took, and how long you took it. Before you start using this medicine, be sure to tell your healthcare provider if you think you are still having withdrawal symptoms. Your body must be opioid-free for 7-10 days before starting naltrexone. If there are still opioids in your system, taking naltrexone can cause sudden and intense withdrawal symptoms.
Naltrexone oral tablets are scored — they have a grooved line to help you break them in half if needed. But check with your doctor before crushing or chewing these tablets. Your doctor may lower your naltrexone dosage if your liver or kidneys aren’t functioning well.
Potential Side Effects of Naltrexone: What You Need to Know
For details about naltrexone dosages, see the “Naltrexone dosage” section. Josh Lee is a clinician and researcher with a focus on medication-assisted treatment of alcohol and opioid use disorders. He has conducted multiple clinical trials examining the use of naltrexone in primary naltrexone side effects care and other community settings. As a practicing physician, Josh helps manage the NYC Health + Hospitals/Bellevue addiction medicine clinic in adult primary care.
Information about Medications for Opioid Use Disorder (MOUD)
Naltrexone https://dainikfaridpurmohanagarbarta.com/2021/01/12/sobriety-anniversary-speech-step-by-step-guide-on/ is an opioid antagonist, meaning it blocks the effects of opioids in the brain. It’s part of a broader, evidence-based approach called medication-assisted treatment (MAT), which combines medication with counseling and wraparound services. Yes, naltrexone works for alcohol addiction because it blocks opioid receptors, reducing the pleasurable effects of alcohol and helping individuals maintain sobriety. It does not stop alcohol withdrawal symptoms but is effective in lowering cravings and preventing relapse.
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