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An important developmental dimension of this loop is relevant to schizophrenia: prenatal or early postnatal GSH deficits during critical windows of glutamatergic circuit maturation impair parvalbumin interneurons development, producing lasting alterations in NMDA receptor subunit composition and EAAT expression that persist into adulthood [125]
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SIDE EFFECTS The most common adverse events reported in clinical trials for Cagrilintide, both as monotherapy and as CagriSema, are primarily gastrointestinal (GI) in nature, typically classified as mild to moderate in severity
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