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NEOLISE's own Telehealth Informed Consent - which this article reviewed and which appears to be a general document covering the brand's broader compound catalog, not exclusively Renewal - states the following about each Renewal peptide specifically: BPC-157: "The FDA has stated it lacks sufficient information to fully characterize the safety profile of BPC-157 when administered to humans." The same document notes BPC-157 "is prohibited under the World Anti-Doping Agency Prohibited List effective January 1, 2022, and may not be used by athletes subject to WADA testing." TB-500: "The FDA has stated it lacks sufficient information to know whether the substance would cause harm when administered to humans." NEOLISE's consent document states TB-500 "is prohibited under the World Anti-Doping Agency Prohibited List" as well

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Tgfbr2 silencing in forebrain-derived neural progenitors and neural cells impedes EC migration and sprouting, decreases vessel density and branching via altered secretion of pro- and anti-angiogenic factors, thereby leading to intracerebral hemorrhage in the telencephalon (Hellbach et al., 2014)