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The standard curve ( Figure S6 ) of MET was established based on the absorption spectra of MET at different concentrations (Figure 2I)

Endosomes

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In fact, it has been reported that increased levels of hydroperoxide, which can represent a consequence of MeHg-induced inhibition of glutathione peroxidase (discussed latter, [24]), are able to decrease astrocyte glutamate uptake [25], which may culminate an excitotoxicity and calcium-mediated neuronal damage [23, 26]