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Subsequently, the mGCs were filtered through a 70-mesh sieve, centrifuged (1000 rpm, 8 min), and cultured in DMEM/F12 (11320033, Gibco) supplemented with 10% foetal bovine serum (FBS, A5670701, Gibco)
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These findings highlight HIF isoforms as key regulators of redox balance and suggest that combining HIF-1α inhibitors with ferroptosis inducers could effectively target hypoxic tumors
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