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This process involves the repositioning or restructuring of nucleosomes, thereby changing the accessibility of DNA to transcription factors and regulatory proteins, which in turn affects the expression of NRF2 target genes
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Magnetic resonance imaging (MRI), which is a non-invasive diagnostic method, holds a promise in having the unique ability to potentially detect cartilage lesions, as well as the internal disarrangement in cartilage before macroscopic morphological cartilage loss
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