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As a result, if there is a contribution of diverse caspases to the induction of As 2 O 3 -induced AVO, it is marginal (Fig 6G), whereas 3-MA downregulated As 2 O 3 -induced AO increase, (Fig 6F and 6H), demonstrating that AVO formation induced by As 2 O 3 originates from the autophagy induction
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