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and L.Z.), and the CAS Project for Young Scientists in Basic Research (YSBR-010 to J.W.)
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Therapeutic strategies targeting metabolic reprogramming in HCC Targeting glycolysis: inhibiting the Warburg effect Mode of action: Inhibiting HK2 or PKM2 can reduce lactate secretion, alleviate TME acidification, and reverse the functional inhibition of CD8 + T cells (such as through PD-L1 down-regulation) [155]
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