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Enzyme inactivation is not the only mechanism by which reactive electrophilic analogues of glutathione, such as EdAG, can elicit, disturb or disrupt biological mechanisms
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A better understanding of the multiple molecular mechanisms involved in the cellular action of fumaric acid esters (FAEs) will help to adapt and to further improve the use of such small molecules for the treatment of psoriasis and other chronic inflammatory diseases (6)
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