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Study has proven that TGF-β signaling in retinal endothelial cells is amplified in early DR, promoting collagen cross-linking and basement membrane rigidity (19)
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Concerning the rKOR, the phosphorylation-defective mutant S369E is unable to internalize upon U50,488 exposure demonstrating the role of receptor phosphorylation in endocytosis (Mclaughlin et al., 2003)
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