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In vitro studies have shown that epidermal vitiligo melanocytes have lower adenosine Triphopsphate (ATP), increased proton leakage, and altered expression of several glycolytic enzymes (hexokinase II, pyruvate dehydrogenase kinase 1, and pyruvate kinase M2) compared to healthy cells
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27 Results from in-vitro research suggest that lipoic acid may enhance glucose uptake by helping to regulate the activity of a glucose transporter molecule, which stimulates insulin-signalling mechanisms
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