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[0104] In some embodiments, J is: [0107] In some embodiments, Z is 4-12 membered heterocyclyl optionally substituted with one to three R 7 or 5-12 membered heteroaryl optionally substituted with one to three R 7 , and each R 7 is independently selected from halo, Ci-6 alkyl, -NH2, -SChCCi-s alkyl), -O(Ci-3 alkyl), and C3-6 cycloalkyl, wherein each C1-6 alkyl optionally substituted with one to four halo or -OH or CN