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A similar finding was presented in an Italian retrospective study [64] with 13 out of 37 RCeD patients (35%) with an autoimmune disease, of which 3 (8%) had autoimmune liver disease
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Furthermore, studies using the triple transgenic (3xTg-AD) mouse model have found that chronic Cu exposure induces an increase in tau protein phosphorylation, which can promote or exacerbate the progression of AD (Crouch et al., 2009)
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