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In the derivatization approach, thiol containing metabolites can be stabilized through covalent alkylation with reagents such as N-ethylmaleimide (NEM), iodoacetamide (IAM), and iodoacetic acid (IAA)
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Results Development of a computational workflow to predict viral replication capacities and antiviral targets We developed a computational workflow to reconstruct the metabolic state of virally infected cells, leveraging single-cell sequencing gene expression data (Methods)
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