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Conditions such as schizophrenia, OCD, personality and behaviour disorders, intellectual disability, autism, ADHD, conduct disorder, and tic disorder showed the highest risk following infection ( Studies on antibiotic use during pregnancy and the early postpartum period show that in children aged 8–14, the risk associated with antibiotic use varies, indicating a 30%–120% increased likelihood of developing autism spectrum disorder or infantile autism, depending on the class of antibiotic used ( Antibiotic exposure during the fetal period and the first two postnatal years was associated with a 10%–50% increased risk of developing various psychiatric disorders by age 18, including mood and anxiety disorders, sleep disorders, ADHD, and conduct disorders ( A follow-up study of 526 children up to age 11, where 70% had antibiotic use in the first year of life, revealed more behavioural difficulties and symptoms of depression

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43 This process is transcription‐dependent and involves p53 activity