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A standard intravenous N-acetylcysteine protocol was started with 150 mg/kg of N-acetylcysteine mixed in 12 mL of 5% dextrose (3 mL/kg) and infused over 60 minutes, followed by 50 mg/kg of N-acetylcysteine mixed in 40 mL of 5% dextrose (10 mL/kg) and infused over 4 hours, then 100 mg/kg of N-acetylcysteine in 80 mL of 5% dextrose (20 mL/kg) infused over 16 hours
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Similarly, trauma induced increased Flavonifractor may potentially compromise GABA availability, since these bacteria primarily utilize GABA for metabolism (Tanelian et al., 2023) potentially affecting this key inhibitory neurotransmitter and contributing to anxiety symptoms observed in PTSD (Strandwitz et al., 2018)
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