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Moreover, mutations in GBA impair lysosomal enzyme activity and acidification, leading to defective autophagic flux [173]
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over 60 years old Angelica Sharma* 1 , Aravinth Sivagnanaratnam 1 1 Northwick Park Hospital, London North West NHS Trust, Stroke Unit, London, United Kingdom Background and aims: Incidence of stroke in young adults is rising, with 15-25% of cases occurring in those aged 60 years (‘old-age stroke’[OS])
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