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CTL019 (tisagenlecleucel): CAR-T therapy for relapsed and refractory B-cell acute lymphoblastic leukemia
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To counteract this, fibrosarcoma cells activate parallel antioxidant systems: GPX4 reduces toxic lipid peroxides to inert lipid alcohols using glutathione, while ferroptosis suppressor protein (FSP1/AIFM2) regenerates reduced coenzyme Q10 and vitamin K, both of which act as radical-trapping antioxidants 102,103,104 )
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