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Interestingly, the infiltration of Th1 and Th17 cells into the CNS, as well as the secretion of cytokines by CD4+ T cells, could also be initiated by ferroptotic neurons, which were induced by over-expression of ACSL4 (a regulator of PUFA-PLs synthesis) (58)
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Rennin, an angiotensin enzyme, is a major contributor to blood pressure regulation and the development of conditions like hypertension, renal disease, and other cardiovascular disorders
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