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GLUL variants and cardiovascular health Some GLUL gene variants have also been linked to an increased risk of cardiovascular health problems, such as coronary artery disease, heart attack and stroke
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It’s also far too simplistic to assume that increasing methyl donors like folate and other B vitamins will inevitably lead to hypermethylation because the control of methylation is complex, involving DNA-methyltransferases, histones, and other regulatory proteins ( 4 )
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