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One of these is cellular senescence, a state of irreversible growth arrest accompanied by the acquisition of a senescence-associated secretory phenotype, which entails the release of pro-inflammatory and pro-fibrotic factors
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The reaction buffer contained 10 mM ATP, 5 mM l-glutamic acid, 0.5 mM EDTA, 5 mM sodium borate, 0.5 mM serine, 10 mM MgCl 2 , and reaction was started with 0.5 mM l-cysteine
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