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Simvastatin, a semisynthetic lipophilic HMG-CoA reductase inhibitor, has demonstrated anti-fibroid properties by inhibiting fibroid cell proliferation, decreasing the expression of proliferative markers such as Ki67, and promoting apoptosis of fibroid cells (in a dose-dependent manner) in in vitro studies [81,83]
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Proc Nutr Soc (2020), 1–11
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