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The Therapeutic Potential of Antioxidants in Chemotherapy-Induced Peripheral Neuropathy: Evidence from Preclinical and Clinical Studies - Neurotherapeutics
MDM2-p53 (PPI): Selective Pressure on TP53 and MDM4 MDM2 inhibitors in tumors with wild-type TP53 exert selective pressure that can favor the emergence of TP53-mutant clones and limit response durability, thereby supporting the development of intermittent dosing schedules and combination strategies (e.g., with cytotoxic agents, tyrosine kinase inhibitors, or immunotherapy) [274,333]
Procolageno
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ENL-Q41A was not degraded by ENL YEATS domain ligands (SR-0813 and TM-7) or inactive analogs of dHCT1 ( 5 and 6 ) (Extended Data Fig
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