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In terms of clinical translation, although current results indicate variability in the improvement of UPDRS scores with hydrogen interventions, such as hydrogen-rich water or inhalation, its safety profile underscores its unique potential as an adjunctive therapy

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A lack of intracellular cysteine, GSH, or SLC7A11 suppression reduces GPX4 activity, which can enhance lipid peroxidation and trigger ferroptosis (47)