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What is more, a recent study revealed that luteolin significantly downregulates the expression of four genes (AP2B1, APP, GPNMB, and DLST), which are associated with drug resistance, cell proliferation, macrophages, apoptosis, and HDAC inhibition and are highly expressed in breast cancer cells [80]
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This kind of targeted therapy could potentially lower the number of side effects that can come with altering glutathione levels across the whole body
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