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6,7   FDA warns against the use of injectable glutathione as a skin whitener because whitening is not an approved use,9  efficacy is not well-established, and there have been reported side effects (acute renal failure, severe drug reactions such as generalized morbilliform eruption with angioedema and urticaria, vasculitis, anaphylactic shock and many documented side effects based on studies on IV glutathione used as skin whitening).6,7,8, 12

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FIGURE 5 Elution buffer ionic strength and pH were investigated at a fixed 1 mM GSH concentration using a NaCl elution gradient from 0–100 mM NaCl at pH 7, 8, and 9 with a microcarrier CB produced using 34°C and 37°C infections

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