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CD38 is also one of the three ectoenzymes in the CD38/CD203a/CD73 pathway that produces ADO, which not only regulates immune response in hypoxic conditions but also suppresses the antitumor immune response by recruiting MDSCs and Treg cells, inhibiting the activity of T effector cells and thus favoring tumor progression
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In the process of studying its biological effects, scientists found that the level of GHK-Cu declines with age, leading them to conduct further studies on the effect of GHK-CU on maintaining healthy tissues
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