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Funding: This work was supported by a Grant-in-aid Special Project Research on Cancer-Bioscience [grant number 17014020] from the Ministry of Education, Culture, Sports, Science and Technology of Japan
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Unlike acetylation, methylation can either suppress or activate gene expression, depending on the site and degree of methylation
since it is of essential importance for overall health and given the fact that no one is exempt from the reduction of this important substance which occurs naturally with age
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