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Measurement of antioxidant enzyme activities All the enzyme activities were measured using commercially available test kits
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HIV-1 Tat-mediated microglial senescence by miRNA-505-SIRT3 pathway Senescence was initially defined as the cessation of cell division after multiple replication cycles [62] and has expanded to include premature senescence triggered by telomere shortening, oxidative stress, mitochondrial dysfunction, and lysosomal alterations [63]
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