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Animal cells also respond against oxidative stress by enhancing their PPP-directed NADPH production
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Treating 2K-1C rats with doxycycline, a broad MMP inhibitor, attenuated MMP-2 activity in the aorta and hypertrophic remodeling, followed by reduction in VSMC proliferation and the resynthesis of collagen and elastin (Castro et al., 2008)
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