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Hallmarks of aging: The trial reported improvements across seven of the nine recognized hallmarks of aging, including markers of mitochondrial dysfunction, genomic damage, cellular senescence, and stem cell exhaustion
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Without ATP, myosin heads remain locked onto actin filaments, unable to detach — this fixed actin-myosin cross-bridge is what physically produces the stiffness of rigor mortis, not a new contraction, but an inability to release an existing one
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