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MYC was found to upregulate glutamine transporters and induce the expression of GLS at the mRNA and protein level 48, 145 , and to drive a glutamine-fueled TCA cycle and glutathione production in hypoxia 151
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142,143 Similarly, OC opacification on computed tomography (CT), reflective of OC patency, has been shown to correlate with OD differentially by CRS type
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