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CD4(+) intraepithelial lymphocytes obtained from transgenic mice prone to develop spontaneous EAE can infiltrate the CNS and ameliorate EAE severity in wild-type mice on transfer, showing regulatory properties (Kadowaki et al
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Adult stem cell-derived organoids have emerged as powerful tools for studying organ-specific biology and disease modeling and they achieved a long-term culture (over 6 months) of primary kidney tubular epithelial organoids, named “tubuloids”
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