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These results all encourage a conclusion that LASSS treatment (at 1:8000 ratio to HGF) may enhance the c-met binding-affinity of HGF without disturbing HGF-c-Met signaling and that this enhancement occurs through a mechanism that is unrelated to prevention of HGF nitration
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The gut microbiota regulates the metabolism and side effects of irinotecan (CPT-11), a topoisomerase inhibitor prodrug of SN-38 that is frequently used to treat colorectal cancer (Wallace et al., 2018)
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