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The GH–IGF Axis in Human Growth Physiology of GH and the IGF-I system in relation to linear growth The actions of GH are mediated by a combination of components of the IGF system, including IGF-I, IGF-binding proteins (IGFBPs), the IGF-I receptor (IGFIR), and IGF-independent effects through direct GH action
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962 Downregulating TMPRSS6 using small interfering RNA (siRNA) induces hepcidin expression, reducing tissue and serum iron levels in Hbb th3/+ mice
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