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Prolonged high levels of IL-6 observed in pediatric obesity or chronic inflammatory conditions, lead to the premature depletion of osteoprogenitor reserves, increased marrow adiposity, and impaired bone accrual (77, 84–86)

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In addition, we might also extrapolate the results of this study to hypothesise that, while studying a disease involving a gene family with high sequence homology and overlapping substrate specificity, the examination of only one gene will not provide the proper insight of the disease in question, as multiple numbers of gene families can function simultaneously