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Methods: A tumor microenvironment (TME)-responsive PFC/TRIM37@Fe-TA@HA (abbreviated as PTFTH) nanoplatform was constructed by coating Fe 3+ and tannic acid (TA) on the surface of TRIM37-siRNA loaded phase-transition perfluorocarbon (PFC) nanodroplets and further modifying them with hyaluronic acid (HA) to achieve tumor-specific mild photothermal/gene/ferroptosis synergistic therapy (MPTT/GT/ Ferroptosis) in vitro
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Your own tissue: Bone Marrow Concentrate: Harvested from your own bone marrow Concentrated to 5-10x normal stem cell density Ideal for severe cartilage damage or osteoarthritisβ Conditions Best Treated with Stem Cell Therapy: Moderate to severe plantar fasciitis (failed conservative treatment) Achilles tendon tears or chronic tendinopathy Ankle and foot joint osteoarthritis Cartilage damage in ankle joint Chronic lateral ankle instability Osteochondral lesions (bone and cartilage defects) What to Expect: DPMx: If choosing donated stem cell products (DPMx), the procedure is performed in the office setting
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