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We used the gene function annotations from the UniProt and Protein Altas databases in Metascape, and screened for genes that encode secreted proteins

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What builds muscle Let's be honest about what matters: Tier 1 (foundation - 80% of results): Progressive overload training Adequate protein (0.8-1g per pound) Caloric surplus (for muscle gain) 7-9 hours sleep Consistency over months/years Tier 2 (optimization - 15% of results): Creatine monohydrate (proven) Proper micronutrients Training periodization Recovery protocols Tier 3 (enhancement - 5% of results): Testosterone replacement (if low) Not on the list : Most OTC testosterone boosters