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For the next measurement pellets are immersed in a buffer not containing ADP and the TL is biased away from ADP pickup and towards ATP transfer into the artificial cytosol at pH = (8.9 ± 0.2) After 10 min the mitochondrial ATP is again measured giving result k, and the factor TL IN is the fractional decrease: l = [(g – k) / g]
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In cases of C3G with concurrent TMA but without MG, the prophylactic use of eculizumab to prevent recurrence may be considered, despite the lack of strong supporting evidence
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