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doi: 10.1016/S2213-8587(18)30348-6
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this results in hepatic injury and subsequent centrilobular liver necrosis Symptoms: 0-24 hrs : asymptomatic pallor anorexia, nausea & vomiting, malaise 18-72 hrs : right upper quadrant abdominal pain rising liver enzymes (AST & ALT) tachycardia hypotension ≥3-4 days : hepatic dysfunction with jaundice recurrence of nausea & vomiting renal failure possible death otherwise after 4 days - 3 weeks : resolution of symptoms
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